Heart & Metabolic Health

Metabolic Syndrome

Metabolic syndrome is a cluster of risk factors that together increase the risk of heart disease, stroke, and type 2 diabetes.

Also known as: insulin resistance syndrome

Updated November 13, 2026 · Patient education

Understanding Metabolic Syndrome

The cluster includes a large waist circumference, high blood pressure, elevated blood glucose, high triglycerides, and low HDL cholesterol. Clinicians generally identify the syndrome when at least three of these factors are present under the applicable criteria.

How it is assessed or used in care

Assessment uses medical history, physical measurements, and blood tests. Exact cutoffs and waist measurements can depend on the guideline and patient population. The diagnosis describes combined risk, not a single disease with one test.

What to discuss with your clinician

Ask which factors apply to you and how the care plan will address each one. Treatment may involve healthier habits and medications for specific conditions. Follow-up matters even when there are no symptoms.

Medical references

  1. Metabolic Syndrome - What Is Metabolic Syndrome? | NHLBI, NIH

Sources accessed November 13, 2026.

This information is for general education, not a diagnosis or an individualized treatment plan. Discuss symptoms, test results, and treatment decisions with a qualified clinician. For a medical emergency, call 911.